
Fitzgerald/MDM2 antibody/10-2548/100 ug
商品编号:
10-2548-100ug
品牌:
fitzgerald-fii
市场价:
¥3900.00
美元价:
2925.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | Monoclonal MDM2 antibody, Anti-MDM2 antibody, 1700007J15Rik, AA415488, Double minute 2 protein, E3 ubiquitin-protein ligase Mdm2, Mdm-2, Mdm2, Oncoprotein Mdm2, OTTMUSP00000022916, p53-binding protein Mdm2, transformed mouse 3T3 cell double minute 2 antibody |
---|---|
Specificity | Human |
Applications | ELISA, IF, IHC, IP, WB |
Immunogen | MDM2 antibody was raised in Mouse using synthetic peptide CSRPSTSSRRRAISE (residues 154-167 in human MDM2) cross-linked to KLH using glutaldehyde as the immunogen |
SPECIFICATIONS:
Host | Mouse |
---|---|
Clone | SMP 14 |
Isotype | IgG2a |
Method of Purification | MDM2 antibody purified by affinity chromatography |
Form & Buffer | Supplied as liquid in PBS with 0.02% sodium azide |
Concentration | 1 mg/ml |
STORAGE & SAFETY:
Storage | Store as concentrated solution. Aliquot and store at -20 deg C or below. Avoid repeated freeze-thaw cycles. |
---|
GENERAL INFORMATION:
Biological Significance | MDM2 is a ubiquitin ligase for p53, plays a central role in regulation of the stability of p53 via Akt-mediated MDM2 phosphorylation. Phosphorylation of MDM2 increases its interaction with p300, providing a platform to allow the assembly of the protein complex necessary for MDM2-mediated ubiquitination and degradation of p53. |
---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
联络我们