Fitzgerald/DHFR antibody/10R-11453/50 ul
商品编号：
10R-11453-50ul
品牌：
fitzgerald-fii
市场价：
¥3900.00
美元价：
2925.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal DHFR antibody, Anti-DHFR antibody, Dihydrofolate reductase antibody, EC 1513 |
|---|---|
| Applications | ELISA, WB |
| Immunogen | DHFR antibody was raised in Mouse using recombinant human DHFR (1-187aa), purified from E. coli, as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | AT5B2 |
| Isotype | IgG1 kappa |
| Method of Purification | DHFR antibody was purified by protein A affinity chromatography |
| Form & Buffer | Supplied in liquid form in Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Concentration | 1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage or -20 deg C for long term storage |
|---|
GENERAL INFORMATION:
| Biological Significance | Dihydrofolate reductase (DHFR) catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, and is a crucial enzyme for the synthesis of purines, pyrimidines and some amino acids. Inhibition of the activity of this enzyme leads to arrest of DNA synthesis and cell death. Gene expression of methotrexate (MTX)-resistant variants of DHFR in normal hematopoietic cells is a potential strategy to permit administration of larger doses of MTX by alleviating drug toxicity in normal cells and tissues that are drug sensitive. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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