菲茨杰拉德/KRT5抗体/10R-11445/50微升
商品编号：
10R-11445-50ul
品牌：
fitzgerald-fii
市场价：
¥3900.00
美元价：
2925.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal KRT5 antibody, Anti-KRT5 antibody, Keratin 5 antibody, CK5 antibody, DDD antibody, K5 antibody, KRT5A |
|---|---|
| Applications | ELISA, WB |
| Immunogen | KRT5 antibody was raised in Mouse using recombinant human KRT5 (1-590aa), purified from E. coli, as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | AT12C4 |
| Isotype | IgG2a kappa |
| Method of Purification | KRT5 antibody was purified by protein A affinity chromatography |
| Form & Buffer | Supplied in liquid form in Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Concentration | 1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage or -20 deg C for long term storage |
|---|
GENERAL INFORMATION:
| Biological Significance | Keratin 5, also known as KRT5, K5, or CK5, dimerizes with keratin 14 and forms the intermediate filaments(IF) that make up the cytoskeleton of basal epithelial cells. This protein is involved in several diseases including epidermolysis bullosa simplex and breast and lung cancers. Keratin 5(and K14) are expressed primarily in basal keratinocytes in the epidermis, specifically in the stratified epithelium lining the skin and digestive tract. Keratin intermediate filaments make up the cytoskeletal scaffold within epithelial cells, which contributes to the cell architecture and provides the cells with the ability to withstand mechanical, and non-mechanical, stresses. K5/K14 keratin pairs are able to undergo extensive bundling due to the non-helical tail of K15 acting as a weak cross-linker at the intermediate filament surface. This bundling increase the elasticity, and therefore the mechanical resilience, of the intermediate filaments. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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