Fitzgerald/Phospho-Rb (SER780) antibody/10R-P122a/100 ug
商品编号：
10R-P122a-100ug
品牌：
fitzgerald-fii
市场价：
¥10500.00
美元价：
7875.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal Phospho-Rb (SER780) antibody, Anti-Phospho-Rb (SER780) antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | To be determined by end-user |
| Applications | WB |
| Immunogen | Phospho-Rb (SER780) antibody was raised in mouse using synthetic human phosoho-RB(ser780) peptide, TRPPTLS(PO3)PIPHIP, which corresponds to amino acids 774-786 of human pRB as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 2C4 |
| Isotype | IgG1 |
| Form & Buffer | Supplied as a lyophilized powder. Reconstitute in 100 ul of distilled water. |
STORAGE & SAFETY:
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze-thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | WB: 1 ug/ml |
|---|
GENERAL INFORMATION:
| Biological Significance | Cyclin-dependent kinases (Cdks) play important roles in the regulation of the cell cycle. RB protein (pRB) is phosphorylated by cyclin D-Cdk4/Cdk6 and cyclin A/cyclin E-Cdk2 during the G1/S transition. This phosphorylation causes the inactivation of the growth inhibitory functions of pRB. pRB undergo phosphorylation and attendant functional inactivation, the cell proceed into late G1. Cyclin D-Cdk4 specifically phosphorylates Ser780 in pRB, while cyclin E-Cdk2 and cyclin A-Cdk2 does not. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
联络我们
