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当前位置: 首页 > 产品中心 > Functional_antibody > Fitzgerald/MIP1 alpha antibody/10-M11A/500 ug
商品详细Fitzgerald/MIP1 alpha antibody/10-M11A/500 ug
Fitzgerald/MIP1 alpha antibody/10-M11A/500 ug
Fitzgerald/MIP1 alpha antibody/10-M11A/500 ug
商品编号: 10-M11A-500ug
品牌: fitzgerald-fii
市场价: ¥5480.00
美元价: 4110.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

OVERVIEW:

Synonyms Monoclonal MIP1 alpha antibody, Anti-MIP1 alpha antibody, MIP 1 alpha antibody, Macrophage Inflammatory antibody-1 alpha antibody, MIP 1 alpha, MIP1 alpha, LD78 beta antibody, MIP-1 alpha antibody, MIP-1 alpha antibody, MIP-1 alpha, CCL3 antibody
Specificity Human MIP1
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen MIP1 alpha antibody was raised in mouse using highly pure recombinant human MIP-1 alpha as the immunogen.
Assay Information This can be used as the capture antibody in sandwich ELISA assays with 60R-MG001bt as thedetection antibody.

SPECIFICATIONS:

Host Mouse
Clone M6110647
Isotype IgG1 kappa
Method of Purification MIP1 alpha antibody was purified by Protein A chromatography from cell culture.
Molecular Weight 7.8 kDa (predicted detection band MW)
Form & Buffer Supplied lyophilized fromPBS buffer, pH 7.2.

STORAGE & SAFETY:

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

Usage Assay Information:

Usage Recommendations ELISA: 2-4 ug/ml, Inhibition: 5-10 ug/ml, WB: 2-4 ug/ml

GENERAL INFORMATION:

Biological Significance Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and Mouse MIP-1 alpha and MIP-1 beta are active on human and Mouse hematopoietic cells.
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。