Fitzgerald/Calcineurin B antibody/10R-C107B/100 ug
商品编号：
10R-C107B-100ug
品牌：
fitzgerald-fii
市场价：
¥9080.00
美元价：
6810.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal Calcineurin B antibody, Anti-Calcineurin B antibody |
|---|---|
| Specificity | Human calcineurin B |
| Cross Reactivity | Human, mouse, rat |
| Applications | WB |
| Immunogen | Calcineurin B antibody was raised in mouse using E. coli-derived recombinant human calcineurin B as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 323417 |
| Isotype | IgG2a |
| Form & Buffer | Lyophilized from a 0.2 u filtered solution in PBS with 5% trehalose. Reconstitute with sterile PBS. |
STORAGE & SAFETY:
| Storage | Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | WB: 0.5 ug/ml |
|---|
GENERAL INFORMATION:
| Biological Significance | Calcineurin (CN) is a protein phosphatase also known as protein phosphatase 3, PPP3CA, and formerly known as protein phosphatase 2B (PP2B). It activates the T cells of the immune system and can be blocked by drugs. Calcineurin activates NFATc (Nuclear Factor of Activated T cell, cytoplasmic), a transcription factor, by dephosphorylating it. The activated NFATc is then translocated into the nucleus, where it upregulates the expression of interleukin 2 (IL-2), which, in turn, stimulates the growth and differentiation of T cell response. Calcineurin is the target of a class of drugs called calcineurin inhibitors, which includes ciclosporin, pimecrolimus and tacrolimus. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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