Fitzgerald/IL33 antibody/10R-1085/100 ul
商品编号：
10R-1085-100ul
品牌：
fitzgerald-fii
市场价：
¥5300.00
美元价：
3975.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal IL33 antibody, Anti-IL33 antibody, IL-33, Interleukin 33 precursor antibody, IL 33 antibody, IL-33 antibody, NKHEV antibody, NF HEV antibody, IL 33 antibody, NF-HEV antibody, INTERLEUKIN 33 NFHEV antibody, Nuclear factor from high endothelial venules antibody, IL1F11 antibody, DVS27 antibody, RP11 575C20.2 antibody, Interleukin33 antibody, Interleukin 33 CHROMOSOME 9 OPEN READING FRAME 26 antibody, Interleukin 1 family member 11 antibody, IL33, DVS27 related protein antibody, IL-33 antibody, IL 33, IL 1F11 antibody, Interleukin 33 antibody, DKFZp586H0523 antibody, C9orf26 antibody, il33 antibody, NFHEV antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | To be determined by end-user. |
| Applications | ELISA, WB |
| Immunogen | IL33 antibody was raised in mouse using recombinant human IL-33 (112-270aa) purified from E. coli as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 4E9 |
| Isotype | IgG2b kappa |
| Source | Anti-human IL-33 antibody, clone 4E9, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human IL-33 protein. |
| Method of Purification | IL33 antibody was purified by protein-G affinity chromatography |
| Form & Buffer | Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3. |
| Concentration | 1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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Usage Assay Information:
| Usage Recommendations | WB: 1:500-1:1,000 |
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GENERAL INFORMATION:
| Biological Significance | Interleukin 33 (IL-33) is a 32kDa proinflammatory cytokine and intracellular nuclear factor with transcriptional regulatory properties. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12kDa and C-terminal fragment of 18kDa by cleavage of caspase-1. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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