Fitzgerald/Nicastrin antibody/10R-1141/100 ul
商品编号：
10R-1141-100ul
品牌：
fitzgerald-fii
市场价：
¥5300.00
美元价：
3975.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal Nicastrin antibody, Anti-Nicastrin antibody, APH2 antibody, APH2 antibody, Nicastrin antibody, KIAA0253 antibody, Anti Nicastrin antibody , nicastrin precursor antibody, KIAA0253 antibody, nicastrin antibody, nicastrin antibody, nicastrin precursor antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | Human, Mouse |
| Applications | ELISA, WB |
| Immunogen | Nicastrin antibody was raised in mouse using recombinant human Nicastrin (34-153aa) purified from E. coli as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | AT3B2 |
| Isotype | IgG2b kappa |
| Source | Anti-human Nicastrin antibody, clone AT3B2, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Nicastrin protein. |
| Method of Purification | Nicastrin antibody was purified by protein-G affinity chromatography |
| Form & Buffer | Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3. |
| Concentration | 1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | WB: 1:500-1:1,000 |
|---|
GENERAL INFORMATION:
| Biological Significance | Nicastrin is a large protein that is a component of an enzyme called gamma-secretase, which is lodged in the cell's membrane. Nicastrin protein is physically associated with presenilin and plays an important role in stabilization and correct localization of presenilin to the membrane-bound gamma-secretase complex. Nicastrin also serves as a docking site for gamma-secretase substrates such as APP and Notch, directly binding to them and presenting them properly to gamma-secretase to ensure the correct cleavage process |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
联络我们
