Fitzgerald/EGLN1 antibody/10R-1165/100 ul
商品编号：
10R-1165-100ul
品牌：
fitzgerald-fii
市场价：
¥5300.00
美元价：
3975.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal EGLN1 antibody, Anti-EGLN1 antibody, EGLN 1 antibody, PNAS-137 antibody, HIF prolyl hydroxylase 2 antibody, EGLN1, Prolyl hydroxylase domain-containing protein 2 antibody, EGLN -1 antibody, C1orf12 antibody, PHD2 antibody, egl nine homolog 1 (C. elegans) antibody, HIFPH2 antibody, HPH-2 antibody, EGLN 1, SM-20 antibody, EGLN -1, ZMYND6 antibody, HIF prolyl hydroxylase 2 antibody, SM20 antibody, HIF-PH2 antibody, DKFZp761F179 antibody, PNAS-118 antibody, ECYT3 antibody, Hypoxia-inducible factor prolyl hydroxylase 2 antibody, HPH2 antibody, EGL nine (C.elegans) homolog 1 antibody, HIF-prolyl hydroxylase 2 antibody, Egl nine homolog 1 antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | To be determined by end-user. |
| Applications | ELISA, IF, WB |
| Immunogen | EGLN1 antibody was raised in mouse using recombinant EGLN1 (271-426aa) purified from E. coli as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | AT21E9 |
| Isotype | IgG2b kappa |
| Source | Anti-human EGLN1 antibody, clone AT1E9, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human EGLN1 protein. |
| Method of Purification | EGLN1 antibody was purified by protein-G affinity chromatography |
| Form & Buffer | Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3. |
| Concentration | 1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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Usage Assay Information:
| Usage Recommendations | IF: 1:500-1:1,000 |
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GENERAL INFORMATION:
| Biological Significance | PHD1 (Egln2), PHD-2 (Egln1), and PHD3 (Egln3) are members of the Egln family of proline hydroxylases. The EGLN family, which are known to be cellular oxygen sensors, initiates the first step of HIF degradation through the VHL/ubiquitin pathway. PHD1 and PHD2 can hydroxylate both proline 402 and proline 564, but PHD3 can only hydroxylate proline 564. In addition to HIF, PHD enzymes have also been shown to catalyze the hydroxylation of RNA polymerase subunits and myogenin. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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