Fitzgerald/NMNAT1 antibody/10R-1183/100 ul
商品编号:
10R-1183-100ul
品牌:
fitzgerald-fii
市场价:
¥5300.00
美元价:
3975.00
产品分类:
单克隆抗体
公司分类:
monoclonal_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | MonoclonalNMNAT1antibody,Anti-NMNAT1antibody,NMNATantibody,NMNAT1,NMNAT-1,PNAT1antibody,NMNAT-1antibody,Nicotinamidenucleotideadenylyltransferase1antibody,NMNAT1,NMNAT1antibody |
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Specificity | Human |
CrossReactivity | Tobedeterminedbyend-user. |
Applications | ELISA,WB |
Immunogen | NMNAT1antibodywasraisedinmouseusingrecombinanthumanNMNAT1(1-279aa)purifiedfromE.Coliastheimmunogen. |
SPECIFICATIONS:
Host | Mouse |
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Clone | AT4A2 |
Isotype | IgG2bkappa |
Source | Anti-humanNMNAT1antibody,cloneAT4A2,isderivedfromhybridizationofmouseF0myelomacellswithspleencellsfromBALB/cmiceimmunizedwitharecombinanthumanNMNAT1protein. |
MethodofPurification | NMNAT1antibodywaspurifiedbyprotein-Gaffinitychromatography |
Form&Buffer | SuppliedasaliquidinPBS,pH7.4,with0.1%NaN3. |
Concentration | 1mg/ml |
STORAGE&SAFETY:
Storage | Storeat4degCforshorttermstorage.Aliquotandstoreat-20degCforlongtermstorage.Avoidrepeatedfreeze/thawcycles. |
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UsageAssayInformation:
UsageRecommendations | WB:1:500-1:1,000 |
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GENERALINFORMATION:
BIOLOGicalSignificance | Nicotinamidemononucleotideadenylyltransferase1isanenzymethatinhumansisencodedbytheNMNAT1gene.ItisanessentialenzymebecauseitcatalyzesthefinalstepofNAD+biosynthesis.Therearethreeisoformsinhumansthatexhibittissue-andorganelle-specificexpression.NMNAT-1islocalizedexclusivelyinthenucleus,whereasNMNAT-2andNMNAT-3arefoundintheGolgiandmitochondria,respectively.NMNAT1constituteanuclearNAD+salvagepathwaywhichregulatesthefunctionsofNAD+-dependentenzymessuchastheproteindeacetylaseSIRT1.NMNAT1protectsneuronsfromneuronalactivityinduceddegeneration. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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