菲茨杰拉德/CBFA2T2抗体/10R-1199/50微克
商品编号：
10R-1199-50ug
品牌：
fitzgerald-fii
市场价：
¥8920.00
美元价：
6690.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal CBFA2T2 antibody, Anti-CBFA2T2 antibody, Core-binding factor runt domain alpha subunit 2 antibody, CBFAT 2, CBFAT-2 antibody, CBFAT-2, MTGR1 antibody, CBFAT 2 antibody, ZMYND3 antibody, CBFA2T2, EHT antibody |
|---|---|
| Specificity | Human CBFA2T2 |
| Cross Reactivity | Human. Other species not studied |
| Applications | Dot Blot, FC, ICC, WB |
| Immunogen | CBFA2T2 antibody was raised in mouse using recombinant Core-Binding Factor,Alpha Subunit 2 |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | CBF5I134 |
| Isotype | IgG1 |
| Method of Purification | CBFA2T2 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. |
| Form & Buffer | CBFA2T2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3). |
| Concentration | 100 ug/ml |
STORAGE & SAFETY:
| Storage | Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing. |
|---|---|
| Biohazard Information | This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv |
Usage Assay Information:
| Usage Recommendations | WB: 0.2-2 ug/ml, FC: 0.5-2 ug/sample, ICC: 2-100 ug/ml |
|---|
GENERAL INFORMATION:
| Biological Significance | In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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