Fitzgerald/TYMS antibody/10R-1166/100 ul
商品编号：
10R-1166-100ul
品牌：
fitzgerald-fii
市场价：
¥5300.00
美元价：
3975.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal TYMS antibody, Anti-TYMS antibody, Tsase antibody, TMS antibody, Anti TYMS antibody , TYMS protein antibody, TYMS antibody, MGC88736 antibody, TYMS protein antibody, Tyms thymidylate synthetase antibody, d TMP synthase antibody, EC 2.1.1.45 antibody, HST422 antibody, Thymidylate synthetase antibody, HST422 antibody, TS antibody, MGC88736 antibody, Thymidylate synthase antibody, TYMS antibody, TYMS antibody, EC 2.1.1.45 antibody, Thymidylate synthase antibody, TS antibody, Tyms thymidylate synthetase antibody, TMS antibody, Thymidylate synthetase antibody, Tsase antibody, d TMP synthase antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | To be determined by end-user. |
| Applications | ELISA, IF, WB |
| Immunogen | TYMS antibody was raised in mouse using recombinant TYMS (1-313aa) purified from E. coli as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | AT21S5 |
| Isotype | IgG2b kappa |
| Source | Anti-human TYMS antibody, clone AT1S5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TYMS protein. |
| Method of Purification | TYMS antibody was purified by protein-G affinity chromatography |
| Form & Buffer | Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3. |
| Concentration | 1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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Usage Assay Information:
| Usage Recommendations | IF: 1:500-1:1,000 |
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GENERAL INFORMATION:
| Biological Significance | The methylation of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dMTP) is an essential step for the formation of thymine nucleotides. This process is catalyzed by thymidylate synthase (TS or TYMS). TYMS is an intracellular enzyme that provides the sole de novo source of thymidylate in proliferating cells. Being the exclusive source of dTMP, TS is also an important target for anticancer agents such as 5-fluorouracil (5-FU). 5-FU acts as a TS inhibitor and is active against solid tumors such as colon, breast, head and neck. TS expression may be useful in predicting overall patient survival, but the prognostic value of TS expression continues to be a subject of investigation for different types of cancers. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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