Fitzgerald/LDHA antibody/10R-1177/100 ul
商品编号：
10R-1177-100ul
品牌：
fitzgerald-fii
市场价：
¥5300.00
美元价：
3975.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal LDHA antibody, Anti-LDHA antibody, Lactate dehydrogenase M antibody, Lactate dehydrogenase A4 antibody, Proliferation-inducing gene 19 antibody, l7R2 antibody, A chain antibody, LDHM antibody, GSD11 antibody, LDH1 antibody, LDH muscle subunit antibody, Proliferation-inducing gene 19 antibody, OTTMUSP00000017774 antibody, A chain antibody, Lactate dehydrogenase A antibody, L-lactate dehydrogenase A chain Cell proliferation-inducing gene 19 protein antibody, Renal carcinoma antigen NY-REN-59. antibody, M LDH antibody, Lactate dehydrogenase M antibody, L lactate dehydrogenase A chain antibody, L lactate dehydrogenase A chain antibody, LDHA antibody, GSD11 antibody, Anti LDHA antibody , LDH muscle subunit antibody, OTTMUSP00000017774 antibody, Lactate dehydrogenase 1 antibody, LDHM antibody, Renal carcinoma antigen NY-REN-59. antibody, PIG19 antibody, l7R2 antibody, LDH1 antibody, M LDH antibody, Lactate dehydrogenase A antibody, LDH muscle subunit antibody, L-lactate dehydrogenase A chain Cell proliferation-inducing gene 19 protein antibody, Lactate dehydrogenase A4 antibody, Lactate dehydrogenase 1 antibody, LDH muscle subunit antibody, PIG19 antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | To be determined by end-user. |
| Applications | ELISA, IF, WB |
| Immunogen | LDHA antibody was raised in mouse using recombinant human LDHA (1-332aa) purified from E.coli as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | AT1A4 |
| Isotype | IgG2b kappa |
| Source | Anti-human LDHA antibody, clone AT1A4, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human LDHA protein. |
| Method of Purification | LDHA antibody was purified by protein-G affinity chromatography |
| Form & Buffer | Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3. |
| Concentration | 1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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Usage Assay Information:
| Usage Recommendations | IF: 1:500-1:8,000, WB: 1:500-1:8,000 |
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GENERAL INFORMATION:
| Biological Significance | Lactate through lactate dehydrogenase A (LDHA), which is encoded by a target gene of c-Myc and hypoxia-inducible factor (HIF-1). LDHA expression is repressed by SugR in the absence of sugar. Reduction of LDHA causes bioenergetic and oxidative stress leading to cell death. LDHA (LDH-5, M-LDH, or A4), which is the predominant form in skeletal muscle, kinetically favors the conversion of pyruvate to lactate. Therefore, LDH-A is an attractive target for cancer therapy since its expression is largely relegated to skeletal muscle. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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