Fitzgerald/ELF3 antibody/10R-1244/50 ug
商品编号：
10R-1244-50ug
品牌：
fitzgerald-fii
市场价：
¥8920.00
美元价：
6690.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal ELF3 antibody, Anti-ELF3 antibody, E74-like factor 3 antibody, ESE-1 antibody, ELF 3 antibody, ELF 3, ELF-3, ELF-3 antibody, ESX antibody, EPR-1 antibody, ERT antibody, ELF3 |
|---|---|
| Specificity | Human ELF3 |
| Cross Reactivity | Human. Other species not studied |
| Applications | Dot Blot |
| Immunogen | ELF3 antibody was raised in mouse using recombinant E74-Like Factor 3 (Ets Domain Transcription Factor,Epithelial-Specific ) (Elf3) |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | ELF3B10C4 |
| Isotype | IgG1 |
| Method of Purification | ELF3 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. |
| Form & Buffer | ELF3 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ). |
| Concentration | 100 ug/ml |
STORAGE & SAFETY:
| Storage | Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing. |
|---|---|
| Biohazard Information | This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv |
Usage Assay Information:
| Usage Recommendations | To be optimized by the end user. |
|---|
GENERAL INFORMATION:
| Biological Significance | ELF3 is a transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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