Fitzgerald/BCAS3 antibody/10R-1295/50 ug
商品编号：
10R-1295-50ug
品牌：
fitzgerald-fii
市场价：
¥8920.00
美元价：
6690.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal BCAS3 antibody, Anti-BCAS3 antibody, MGC4973 antibody, Breast carcinoma amplified sequence 3 antibody, BCAS-3, GAOB1 antibody, MAAB antibody, FLJ20128 antibody, BCAS 3, BCAS-3 antibody, BCAS3, BCAS 3 antibody |
|---|---|
| Specificity | Human BCAS3 |
| Cross Reactivity | Human, Mouse, Rat. Other species not studied |
| Applications | Dot Blot, FC, ICC, WB |
| Immunogen | BCAS3 antibody was raised in mouse using recombinant Human Breast Carcinoma Amplified Sequence 3 (Bcas3) |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 2066C2a |
| Isotype | IgG1 |
| Method of Purification | BCAS3 antibody was purified using protein G column chromatography from culture supernatant of hybridomacultured in a medium containing bovine IgG-depleted(approximately 95%) fetal bovine serum. |
| Form & Buffer | BCAS3 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ). |
| Concentration | 100 ug/ml |
STORAGE & SAFETY:
| Storage | Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing. |
|---|---|
| Biohazard Information | This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv |
Usage Assay Information:
| Usage Recommendations | WB: 0.2-2 ug/ml, FC: 0.5-2 ug/sample, ICC: 2-100 ug/ml |
|---|
GENERAL INFORMATION:
| Biological Significance | Breast carcinoma amplified sequence 3, also known as BCAS3, is a protein which in humans is encoded by the BCAS3 gene. BCAS3 is a gene that is amplified and overexpressed in breast cancer cells. The BCAS3 gene is regulated by estrogen receptor alpha. The PELP1 protein acts as a transcriptional coactivator of estrogen receptor induced BCAS3 gene expression. In addition BCAS3 possesses histone acetyltransferase activity and itself appears to act as a coactivator of ER alpha. Furthermore BCAS3 requires PELP1 to function as a coactivator in ER alpha. Hence BCAS3 apparently is involved in a positive feedback loop leading to ER alphamediated signal amplification. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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