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当前位置: 首页 > 产品中心 > monoclonal_antibody > Fitzgerald/CARD8抗体/10R-1300/50微克
商品详细Fitzgerald/CARD8抗体/10R-1300/50微克
Fitzgerald/CARD8抗体/10R-1300/50微克
Fitzgerald/CARD8抗体/10R-1300/50微克
商品编号: 10R-1300-50ug
品牌: fitzgerald-fii
市场价: ¥8920.00
美元价: 6690.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

OVERVIEW:

Synonyms Monoclonal CARD8 antibody, Anti-CARD8 antibody, DKFZp779L0366 antibody, CARD 8 antibody, CARD8, MGC57162 antibody, KIAA0955 antibody, CARD-8, CARD 8, Caspase recruitment domain family antibody, TUCAN antibody, CARDINAL antibody, DACAR antibody, CARD-8 antibody, NDPP1 antibody
Specificity Human CARD8
Cross Reactivity Human. Other species not studied
Applications Dot Blot, FC, ICC, IP, WB
Immunogen CARD8 antibody was raised in mouse using recombinant Human Caspase Recruitment Domain Family, Member 8 (Card8)

SPECIFICATIONS:

Host Mouse
Clone 2108C2a
Isotype IgG1
Method of Purification CARD8 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer CARD8 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

STORAGE & SAFETY:

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

Usage Assay Information:

Usage Recommendations WB: 0.2-2 ug/ml, IP: 100-500 ug/sample, FC: 0.5-2 ug/sample, ICC: 2-100 ug/ml

GENERAL INFORMATION:

Biological Significance The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。