Fitzgerald/DNMT3B antibody/10R-1355/50 ug
商品编号：
10R-1355-50ug
品牌：
fitzgerald-fii
市场价：
¥3920.00
美元价：
2940.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal DNMT3B antibody, Anti-DNMT3B antibody, DNMTB 3 antibody, DNMTB-3, DNMTB-3 antibody, DNA (cytosine-5-)- methyltransferase 3 beta antibody, M.HsaIIIB antibody, ICF antibody, DNMTB 3, DNMT3B |
|---|---|
| Specificity | Human DNMT3B |
| Cross Reactivity | Human, Mouse, Rat. Other species not studied |
| Applications | Dot Blot, FC, ICC, WB |
| Immunogen | DNMT3B antibody was raised in mouse using recombinant Human Dna (Cytosine-5-)-Methyltransferase 3 Beta (Dnmt3B) |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 2280C3a |
| Isotype | IgG2b |
| Method of Purification | DNMT3B antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. |
| Form & Buffer | DNMT3B antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ). |
| Concentration | 100 ug/ml |
STORAGE & SAFETY:
| Storage | Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing. |
|---|---|
| Biohazard Information | This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv |
Usage Assay Information:
| Usage Recommendations | WB: 0.2-2 ug/ml, FC: 0.5-2 ug/sample, ICC: 2-100 ug/ml |
|---|
GENERAL INFORMATION:
| Biological Significance | CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Six alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
联络我们
