Fitzgerald/DFFB antibody/10R-1361/50 ug
商品编号:
10R-1361-50ug
品牌:
fitzgerald-fii
市场价:
¥8920.00
美元价:
6690.00
产品分类:
单克隆抗体
公司分类:
monoclonal_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | Monoclonal DFFB antibody, Anti-DFFB antibody, DFF-40 antibody, DFF2 antibody, DFF40 antibody, DNA fragmentation factor subunit beta antibody, CAD antibody, CPAN antibody |
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Specificity | Human DFFB |
Cross Reactivity | Human. Other species not studied |
Applications | Dot Blot |
Immunogen | DFFB antibody was raised in mouse using recombinant Human Dna Fragmentation Factor, 40Kda, Beta Polypeptide (Caspase-Activated Dnase) (Dffb) |
SPECIFICATIONS:
Host | Mouse |
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Clone | 2263C6a |
Isotype | IgG1 |
Method of Purification | DFFB antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. |
Form & Buffer | DFFB antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ). |
Concentration | 100 ug/ml |
STORAGE & SAFETY:
Storage | Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing. |
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Biohazard Information | This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv |
Usage Assay Information:
Usage Recommendations | To be optimized by the end user. |
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GENERAL INFORMATION:
Biological Significance | DNA fragmentation factor subunit beta is a protein that in humans is encoded by the DFFB gene. Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40kDa (DFFB) and 45kDa (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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