
Fitzgerald/PRKAR1A antibody/10R-1477/50 ug
商品编号:
10R-1477-50ug
品牌:
fitzgerald-fii
市场价:
¥8920.00
美元价:
6690.00
产品分类:
单克隆抗体
公司分类:
monoclonal_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | Monoclonal PRKAR1A antibody, Anti-PRKAR1A antibody, PRKARA 1 antibody, DKFZp779L0468 antibody, Protein kinase cAMP dependent regulatory type I alpha antibody, PRKARA 1, CNC antibody, PRKAR1A, PRKAR1 antibody, CNC1 antibody, PKR1 antibody, PRKARA-1, PPNAD1 antibody, MGC17251 antibody, CAR antibody, TSE1 antibody, PRKARA-1 antibody |
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Specificity | Human PRKAR1A |
Cross Reactivity | Human. Other species not studied |
Applications | Dot Blot, WB |
Immunogen | PRKAR1A antibody was raised in mouse using recombinant Human Protein Kinase, Camp-Dependent, Regulatory, Type I, Alpha (Tissue Specific Extinguisher 1) (Prkar1A) |
SPECIFICATIONS:
Host | Mouse |
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Clone | 3546C2a |
Isotype | IgG1 |
Method of Purification | PRKAR1A antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. |
Form & Buffer | PRKAR1A antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ). |
Concentration | 100 ug/ml |
STORAGE & SAFETY:
Storage | Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing. |
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Biohazard Information | This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv |
Usage Assay Information:
Usage Recommendations | WB: 0.2-2 ug/ml |
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GENERAL INFORMATION:
Biological Significance | cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMPdependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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