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当前位置: 首页 > 产品中心 > monoclonal_antibody > Fitzgerald/RB antibody/10R-1797/100 ul
商品详细Fitzgerald/RB antibody/10R-1797/100 ul
Fitzgerald/RB antibody/10R-1797/100 ul
Fitzgerald/RB antibody/10R-1797/100 ul
商品编号: 10R-1797-100ul
品牌: fitzgerald-fii
市场价: ¥3900.00
美元价: 2925.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

OVERVIEW:

Synonyms Monoclonal RB antibody, Anti-RB antibody
Cross Reactivity Human
Applications ELISA, IHC
Immunogen RB antibody was raised in Mouse using a purified recombinant fragment of human RB expressed in E. coli as the immunogen.

SPECIFICATIONS:

Host Mouse
Clone 7E4B8
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

STORAGE & SAFETY:

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Usage Assay Information:

Usage Recommendations ELISA: 1:10,000, IHC: 1:200-1:1000

GENERAL INFORMATION:

Biological Significance The RB protein regulates differentiation, apoptosis, and cell cycle control by coordinating the cell cycle at G1-S with transcriptional machinery. During G1, cyclin D-dependent kinase-mediated phosphorylation of RB at Ser-795 marks the conversion of Rb from a transcriptionally repressive, hypophosphorylated state to an inactive, phosphorylated state, which may be sustained through mitosis by differential phosphorylation of up to 16 putative serine or threonine residues. Pediatric cancer retinoblastoma and the formation of other human tumors can be attributed to mutations in the retinoblastoma tumor suppressor gene.
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。