Fitzgerald/PIRH2 antibody/10R-1887/100 ul
商品编号：
10R-1887-100ul
品牌：
fitzgerald-fii
市场价：
¥6900.00
美元价：
5175.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal PIRH2 antibody, Anti-PIRH2 antibody, PIRH-2 antibody, PIRH 2 antibody, P53 induced RING-H2 protein antibody, RCHY1 antibody, PIRH2, PIRH 2, PIRH-2, PIRH 2 antibody, PIRH-2 antibody |
|---|---|
| Cross Reactivity | Human, Rat |
| Applications | ELISA, FC, IF, WB |
| Immunogen | PIRH2 antibody was raised in Mouse using a purified recombinant fragment of human PIRH2 expressed in E. coli as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 1H10 |
| Isotype | IgG1 |
| Form & Buffer | Supplied as a liquid in ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1.0 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | ELISA: 1:10,000, FC: 1:200-1:400, IF: 1:200-1:1000, WB: 1:500-1:2000 |
|---|
GENERAL INFORMATION:
| Biological Significance | PIRH2 forms dimers through its N- and C-terminus in cells. PIRH2 has ubiquitin-protein ligase activity and it binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. The PIRH2 is oncogenic because loss of p53 function contributes directly to malignant tumor development. PIRH2 expression decreases the level of p53, and a decrease of endogenous PIRH2 expression increases p53 levels. PIRH2 is therefore considered, together with MDM2, to act as a negative regulator of p53 function. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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