菲茨杰拉德/4EBP1抗体/10R-1951/100微升
商品编号：
10R-1951-100ul
品牌：
fitzgerald-fii
市场价：
¥8500.00
美元价：
6375.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal 4EBP1 antibody, Anti-4EBP1 antibody, 4EBP1, 4EBP-1, 4EBP-1 antibody, Eukaryotic translation initiation factor 4E-binding protein 1 antibody, MGC4316 antibody, 4E BP1 antibody, 4EBP 1 antibody, 4EBP 1, BP-1 antibody, 4E-BP1 antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Immunogen | 4EBP1 antibody was raised in Mouse using a purified recombinant fragment of 4E-BP1 expressed in E. coli as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 4B6G10 |
| Isotype | IgG1 |
| Form & Buffer | Supplied as a liquid in ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1.0 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000 |
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GENERAL INFORMATION:
| Biological Significance | 4EBP1 which is located on chromosome 8p12, with 118-amino acid protein (about 13kDa). Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1. Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while the phosphorylated form will not. Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. 4EBP1 functions as a translation repressor. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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