Fitzgerald/R spondin1 antibody/10R-1965/100 ul
商品编号:
10R-1965-100ul
品牌:
fitzgerald-fii
市场价:
¥6900.00
美元价:
5175.00
产品分类:
单克隆抗体
公司分类:
monoclonal_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | MonoclonalRspondin1antibody,Anti-Rspondin1antibody,Rspondin-1,Rspondin1antibody,Rspondin1antibody,RSPO1antibody,CRISTIN3antibody,Rspondin1,Rspondin1,R-spondin1antibody,FLJ40906antibody,Rspondin-1antibody |
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CrossReactivity | Human |
Applications | ELISA,WB |
Immunogen | Rspondin1antibodywasraisedinMouseusingapurifiedrecombinantfragmentofRSPO1expressedinE.coliastheimmunogen. |
SPECIFICATIONS:
Host | Mouse |
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Clone | 7A6 |
Isotype | IgG1 |
Form&Buffer | Suppliedasaliquidinasciticfluidcontaining0.03%sodiumazide. |
Concentration | 1.0mg/ml |
STORAGE&SAFETY:
Storage | Storeat4degCforshorttermstorage.Storeat-20degCforlongtermstorage.Avoidrepeatedfreeze/thawcycles. |
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UsageAssayInformation:
UsageRecommendations | ELISA:1:10,000,WB:1:500-1:2000 |
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GENERALINFORMATION:
BIOLOGicalSignificance | Rspondin1isamemberoftheR-spondinfamilyandasecretedactivatorproteinwithtwocystein-rich,furin-likedomainsandonethrombospondintype1domain.Inmice,theproteininducestherapidonsetofcryptcellproliferationandincreasesintestinalepithelialhealing,providingaprotectiveeffectagainstchemotherapy-inducedadverseeffects.Itisanactivatorofthebeta-cateninsignalingcascade,leADIngtoTCF-dependentgeneactivation.ActsbothinthecanonicalWnt/beta-catenin-dependentpathway,possIBLyviaadirectinteractionwithWntproteins,andinaWnt-independentbetacateninpathwaythroughareceptorsignalingpathwaythatmaynotusefrizzled/LRPreceptors.ActsasaligandforfrizzledFZD8andLRP6.MaynegativelyregulatetheTGF-betapathway.Hasaessentialrolesinovarydetermination. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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