Fitzgerald/CHK2 antibody/10R-1978/100 ul
商品编号：
10R-1978-100ul
品牌：
fitzgerald-fii
市场价：
¥7900.00
美元价：
5925.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal CHK2 antibody, Anti-CHK2 antibody, CHK2, CHK 2, CHK-2 antibody, CHK 2 antibody, Checkpoint Homolog 2 antibody, CHK-2 |
|---|---|
| Cross Reactivity | Human |
| Applications | ELISA, IF, IHC, WB |
| Immunogen | CHK2 antibody was raised in Mouse using a purified recombinant fragment of human CHK2 (aa481-531) expressed in E. coli as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 1C12B8 |
| Isotype | IgG2b |
| Form & Buffer | Supplied as a liquid in ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1.0 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | ELISA: 1:10,000, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000 |
|---|
GENERAL INFORMATION:
| Biological Significance | CHK2 is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the encoded protein is known to inhibit Cdc25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1. In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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