Fitzgerald/GSK3 alpha antibody/10R-2025/100 ul
商品编号：
10R-2025-100ul
品牌：
fitzgerald-fii
市场价：
¥7500.00
美元价：
5625.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal GSK3 alpha antibody, Anti-GSK3 alpha antibody, Glycogen synthase kinase 3 alpha antibody, GSK-3 alpha antibody, GSK 3 alpha antibody, GSK3 alpha |
|---|---|
| Cross Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Immunogen | GSK3 alpha antibody was raised in Mouse using a purified recombinant fragment of GSK3 alpha expressed in E. coli as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 6G2F1/6G2F2 |
| Form & Buffer | Supplied as a liquid in ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1.0 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000 |
|---|
GENERAL INFORMATION:
| Biological Significance | Glycogen synthase kinase 3 alpha belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily; GSK3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c jun. GSK3 phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK3 and subsequently inhibits GSK3 acutely leading to the stimulation of glycogen synthesis. GSK3 signaling is performed by two isoforms, GSK3 alpha and GSK3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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