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当前位置: 首页 > 产品中心 > Functional_antibody > Fitzgerald/MuSK antibody/10R-2058/100 ul
商品详细Fitzgerald/MuSK antibody/10R-2058/100 ul
Fitzgerald/MuSK antibody/10R-2058/100 ul
Fitzgerald/MuSK antibody/10R-2058/100 ul
商品编号: 10R-2058-100ul
品牌: fitzgerald-fii
市场价: ¥6900.00
美元价: 5175.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

OVERVIEW:

Synonyms Monoclonal MuSK antibody, Anti-MuSK antibody, MuSK antibody, Anti MuSK antibody, Muscle Specific Kinase antibody, Muscle Specific Kinase antibody
Cross Reactivity Human
Applications ELISA, IF, IHC
Immunogen MuSK antibody was raised in Mouse using purified recombinant extracellular fragment of human MuSK (aa24-209) fused with hIgGFc tag expressed in HEK293 cell line as the immunogen.

SPECIFICATIONS:

Host Mouse
Clone 10A4
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

STORAGE & SAFETY:

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Usage Assay Information:

Usage Recommendations ELISA: 1:10,000, IF: 1:200-1:1000, IHC: 1:200-1:1000

GENERAL INFORMATION:

Biological Significance MuSK is a receptor tyrosine kinase required for the formation of the neuromuscular junction (NMJ). It induces cellular signaling by causing the addition of phosphate molecules to particular tyrosines on itself, and on proteins which bind the cytoplasmic domain of the receptor. It is activated by a nerve-derived proteoglycan called agrin. During development, the growing end of motor neuron axons secrete a protein called agrin, his protein binds to several receptors on the surface of skeletal muscle. The receptor which seems to be required for formation of the neuromuscular junction (NMJ), which comprises the nerve-muscle synapse is called MuSK.
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。