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当前位置: 首页 > 产品中心 > Functional_antibody > Fitzgerald/STAT3 antibody/10R-2073/100 ul
商品详细Fitzgerald/STAT3 antibody/10R-2073/100 ul
Fitzgerald/STAT3 antibody/10R-2073/100 ul
Fitzgerald/STAT3 antibody/10R-2073/100 ul
商品编号: 10R-2073-100ul
品牌: fitzgerald-fii
市场价: ¥6900.00
美元价: 5175.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

OVERVIEW:

Synonyms Monoclonal STAT3 antibody, Anti-STAT3 antibody, MGC16063 antibody, STAT 3, STAT3, Signal transducer and activator of transcription 3 antibody, STAT-3 antibody, APRF antibody, STAT-3, STAT 3 antibody, FLJ20882 antibody
Cross Reactivity Human
Applications ELISA, WB
Immunogen STAT3 antibody was raised in Mouse using a purified recombinant fragment of STAT3 expressed in E. coli as the immunogen.

SPECIFICATIONS:

Host Mouse
Clone 7G3H4
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

STORAGE & SAFETY:

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Usage Assay Information:

Usage Recommendations ELISA: 1:10,000, WB: 1:500-1:2000

GENERAL INFORMATION:

Biological Significance STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。