
Fitzgerald/STAT5B antibody/10R-2214/100 ul
商品编号:
10R-2214-100ul
品牌:
fitzgerald-fii
市场价:
¥6900.00
美元价:
5175.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | Monoclonal STAT5B antibody, Anti-STAT5B antibody, STAT5B, STATB-5 antibody, STATB-5, Signal transducer and activator of transcription 5B antibody, STAT5 antibody, STATB 5 antibody, STATB 5 |
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Cross Reactivity | Human |
Applications | ELISA, WB |
Immunogen | STAT5B antibody was raised in Mouse using a purified recombinant fragment of human STAT5B expressed in E. coli as the immunogen. |
SPECIFICATIONS:
Host | Mouse |
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Clone | 5B3 |
Isotype | IgG1 |
Form & Buffer | Supplied as a liquid in ascitic fluid containing 0.03% sodium azide. |
Concentration | 1.0 mg/ml |
STORAGE & SAFETY:
Storage | Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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Usage Assay Information:
Usage Recommendations | ELISA: 1:10,000, WB: 1:200-1:1000 |
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GENERAL INFORMATION:
Biological Significance | STAT5B is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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