Fitzgerald/beta Amyloid antibody/10R-3011/50 ug
商品编号：
10R-3011-50ug
品牌：
fitzgerald-fii
市场价：
¥13900.00
美元价：
10425.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal beta Amyloid antibody, Anti-beta Amyloid antibody, APPA4 antibody, Amyloid Plaque antibody, Abeta antibody, Amyloid Plaque antibody, beta Amyloid antibody, Amyloid beta antibody, Ab antibody, APPA4 antibody, Amyloid beta antibody, Alzheimer Precursor Protein A4 antibody, Abeta antibody, Ab antibody, Anti beta Amyloid antibody, Alzheimer Precursor Protein A4 antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | To be determined by end-user |
| Applications | IHC, WB |
| Immunogen | Amyloid beta antibody was raised in mouse using a synthetic peptide of a part of human Amyloid beta (1128) as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 12B2 |
| Isotype | IgG1 |
| Source | Supernatant |
| Method of Purification | beta Amyloid antibody was affinity purified with antigen peptide |
| Form & Buffer | Lyophilized product from 1 % BSA in PBS, pH 7.4 containing 0.05 % NaN3, reconstitute with 1 ml of distilled water |
STORAGE & SAFETY:
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at 20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | IHC: 0.251 ug/ml, IP: 45 ug/test, WB: 25 ug/ml |
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GENERAL INFORMATION:
| Biological Significance | Alzheimer's disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid (ABeta) peptide, a 40 to 43 amino acid peptide cleaved from amyloid precursor protein by beta-secretase and gamma-secretase. Increased release of ABeta42 or ABeta43, both of which exibit a greater tendency to aggregate than ABeta40, occurs in individuals expressing certain genetic mutations, ApoE alleles or may involve other undiscovered factors. Many researchers theorize that it is this increased release of ABeta42/ABeta43 which leads to the abnormal deposition of ABeta and the associated neurotoxicity in the brains of affected individuals. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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