Fitzgerald/APP antibody/10R-3016/100 ug
商品编号：
10R-3016-100ug
品牌：
fitzgerald-fii
市场价：
¥13500.00
美元价：
10125.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal APP antibody, Anti-APP antibody, APP Cterminus antibody, Amyloid Precursor Protein antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | To be determined by end-user |
| Applications | IP, WB |
| Immunogen | Amyloid precursor protein antibody was raised in mouse using the Nterminal portion of recombinant human APP as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 10D1 |
| Isotype | IgG1 |
| Source | Supernatant |
| Method of Purification | APP antibody was affinity purified with protein A |
| Form & Buffer | Lyophilized product from 1% BSA in PBS, pH 7.4 containing 0.05% NaN3, reconstitute with 1 ml of distilled water |
STORAGE & SAFETY:
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at 20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | IP: 3 ug/ml, WB: 2 ug/ml |
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GENERAL INFORMATION:
| Biological Significance | Amyloid precursor protein (APP) is precursor protein of Amyloid beta which is major constituent of senile plaque in Alzheimer?s disease. It is known that there are three major isoforms. Processing of APP occurs by two major pathways, non-amyloidogenic pathway and amyloidogenic pathway. The non-amyloidogenic pathway is mediated by alpha and gamma-secretases and gives rise to a large fragment known as soluble APP alpha (sAPPalpha) and a small 3 kDa peptide known as p3. On the other hand, the amyloidogenic pathway is mediated by beta and gamma-secretases and yields soluble APPbeta (sAPPbeta) and Amyloid beta. The physiologic function of APP itself is not clear, however, it is supposed that the function of APP in neuron system is different from that in other organ. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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