菲茨杰拉德/细胞周期蛋白D1抗体/10R-3018/200微克
商品编号：
10R-3018-200ug
品牌：
fitzgerald-fii
市场价：
¥13500.00
美元价：
10125.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal Cyclin D1 antibody, Anti-Cyclin D1 antibody, Cyclin D1, Cyclin D-1, G1/S-specific cyclin-D1 antibody, Cyclin D 1 antibody, Cyclin D 1, BCL-1 oncogene antibdoy, PRAD1 oncogene antibody, Cyclin D-1 antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | To be determined by end-user |
| Applications | IHC, WB |
| Immunogen | Cyclin D1 antibody was raised in mouse using recombinant Human PRAD1/cyclin D1 expressed in E. coli as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 5D4 |
| Isotype | IgG2a |
| Source | Supernatant |
| Method of Purification | Cyclin D1 antibody was affinity purified with protein A |
| Form & Buffer | Lyophilized product from 1% BSA in PBS, pH 7.4 containing 0.05% NaN3, reconstitute with 1 ml of distilled water |
STORAGE & SAFETY:
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at 20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | IHC: 25ug/ml, WB: 25 ug/ml |
|---|
GENERAL INFORMATION:
| Biological Significance | Bcl1/Cyclin D1 belongs to the G1 cyclins and plays a key role in cell cycle regulation during the G1/S transition by cooperating with cyclin-dependent kinases (CDKs). Its overexpression may lead to growth advantage for tumor cells by way of cell cycle progression, and actually it has been reported in various human cancers, e.g., esophageal, breast, and bladder carcinomas. Among hematolymphoid malignancies, cyclin D1 overexpression resulting from translocational activation has also been recognized in a subset of Bchronic lymphocytic leukemia (BCLL), multiple myeloma, splenic marginal zone lymphoma, hairy cell leukemia, and mantle cell lymphoma. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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