4000-520-616
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4000-520-616
当前位置: 首页 > 产品中心 > monoclonal_antibody > 菲茨杰拉德/OGG1抗体/10R-3054/100微克
商品详细菲茨杰拉德/OGG1抗体/10R-3054/100微克
菲茨杰拉德/OGG1抗体/10R-3054/100微克
菲茨杰拉德/OGG1抗体/10R-3054/100微克
商品编号: 10R-3054-100ug
品牌: fitzgerald-fii
市场价: ¥13500.00
美元价: 10125.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

OVERVIEW:

SynonymsMonoclonalOGG1antibody,Anti-OGG1antibody,OGG-1antibody,MUTMantibody,OGG-1,OGG1,OGG1antibody,HMMHantibody,OGG1,8-hydroxoguanineDNAGlycosylaseantibody,8-oxoguanineDNAGlycoslyaseantibody,HOGG1antibody,OGH1antibody,MMHantibody
SpecificityHuman
CrossReactivityMouseMouseHumanybridoma,culturemedium
ApplicationsWB
ImmunogenOGG1antibodywasraisedinmouseusingrecombinanthumanOGG1astheimmunogen

SPECIFICATIONS:

HostMouse
Clone7E2
IsotypeIgG1
SourceSupernatant
MethodofPurificationOGG1antibodywasaffinitypurifiedwithproteinA
Form&BufferLyophilizedproductfrom1%BSAinPBScontaining0.05%NaN3,reconstitutewith1mlofdistilledwater

STORAGE&SAFETY:

StorageStoreat4degCuntilreconstitution.Followingreconstitutionaliquotandfreezeat20degCforlongtermstorage

UsageAssayInformation:

UsageRecommendationsWB:1ug/ml

GENERALINFORMATION:

BIOLOGicalSignificanceOxidativedamagetoDNAhasbeenproposedtohavearoleincancerandageing.Oxygen-freerADIcalsformedduringnormalaerobiccellularmetabolismattackbasesinDNA,and7,8-dihydro8oxoguanine(8oxoG)isoneoftheadductsformed.EukaryoticreplicativeDNApolymerasesreplicateDNAcontaining8oxoGbyinsertinganadenineoppositethelesion;consequently,8oxoGishighlymutagenicandcausesG:CtoT:Atransversions.Geneticstudiesinyeasthaveindicatedaroleformismatchrepairinminimizingtheincidenceofthesemutations.InSaccharomycescerevisiae,deletionofOGG1,encodingaDNAglycosylasethatfunctionsintheremovalof8oxoGwhenpairedwithC,causesanincreaseintherateofG:CtoT:Atransversions.
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。