菲茨杰拉德/OGG1抗体/10R-3054/100微克
商品编号:
10R-3054-100ug
品牌:
fitzgerald-fii
市场价:
¥13500.00
美元价:
10125.00
产品分类:
单克隆抗体
公司分类:
monoclonal_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | MonoclonalOGG1antibody,Anti-OGG1antibody,OGG-1antibody,MUTMantibody,OGG-1,OGG1,OGG1antibody,HMMHantibody,OGG1,8-hydroxoguanineDNAGlycosylaseantibody,8-oxoguanineDNAGlycoslyaseantibody,HOGG1antibody,OGH1antibody,MMHantibody |
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Specificity | Human |
CrossReactivity | MouseMouseHumanybridoma,culturemedium |
Applications | WB |
Immunogen | OGG1antibodywasraisedinmouseusingrecombinanthumanOGG1astheimmunogen |
SPECIFICATIONS:
Host | Mouse |
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Clone | 7E2 |
Isotype | IgG1 |
Source | Supernatant |
MethodofPurification | OGG1antibodywasaffinitypurifiedwithproteinA |
Form&Buffer | Lyophilizedproductfrom1%BSAinPBScontaining0.05%NaN3,reconstitutewith1mlofdistilledwater |
STORAGE&SAFETY:
Storage | Storeat4degCuntilreconstitution.Followingreconstitutionaliquotandfreezeat20degCforlongtermstorage |
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UsageAssayInformation:
UsageRecommendations | WB:1ug/ml |
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GENERALINFORMATION:
BIOLOGicalSignificance | OxidativedamagetoDNAhasbeenproposedtohavearoleincancerandageing.Oxygen-freerADIcalsformedduringnormalaerobiccellularmetabolismattackbasesinDNA,and7,8-dihydro8oxoguanine(8oxoG)isoneoftheadductsformed.EukaryoticreplicativeDNApolymerasesreplicateDNAcontaining8oxoGbyinsertinganadenineoppositethelesion;consequently,8oxoGishighlymutagenicandcausesG:CtoT:Atransversions.Geneticstudiesinyeasthaveindicatedaroleformismatchrepairinminimizingtheincidenceofthesemutations.InSaccharomycescerevisiae,deletionofOGG1,encodingaDNAglycosylasethatfunctionsintheremovalof8oxoGwhenpairedwithC,causesanincreaseintherateofG:CtoT:Atransversions. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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