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当前位置: 首页 > 产品中心 > monoclonal_antibody > Fitzgerald/Osteopontin antibody/10R-3057/100 ug
商品详细Fitzgerald/Osteopontin antibody/10R-3057/100 ug
Fitzgerald/Osteopontin antibody/10R-3057/100 ug
Fitzgerald/Osteopontin antibody/10R-3057/100 ug
商品编号: 10R-3057-100ug
品牌: fitzgerald-fii
市场价: ¥13500.00
美元价: 10125.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

OVERVIEW:

Synonyms Monoclonal osteopontin antibody, Anti-Osteopontin antibody, Uropontin antibody, OPN antibody, Urinary Stone protein antibody, OPN antibody, osteopontin antibody, Secreted Phosphoprotein 1 antibody, , Anti Osteopontin antibody, BNSP antibody, Bone Sialoprotein 1 antibody, BNSP antibody, Uropontin antibody, Nephropontin antibody, SPP-1 antibody, Nephropontin antibody, , Secreted Phosphoprotein 1 antibody, Bone Sialoprotein 1 antibody, Urinary Stone protein antibody, SPP-1 antibody
Specificity Human
Cross Reactivity Rabbit, rat
Applications IHC, WB
Immunogen OPN antibody was raised in mouse using a synthetic peptide corresponding to a portion of the Cterminus of human osteopontin as the immunogen

SPECIFICATIONS:

Host Mouse
Clone 1B20
Isotype IgG
Source Supernatant
Method of Purification Osteopontin antibody was affinity purified with protein A
Form & Buffer Lyophilized product from 1% BSA in PBS containing 0.05% NaN3, reconstitute with 1 ml of distilled water

STORAGE & SAFETY:

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at 20 deg C for long term storage

Usage Assay Information:

Usage Recommendations IHC: 12 ug/ml, WB: 2 ug/ml

GENERAL INFORMATION:

Biological Significance Osteopontin (OPN) is a secreted glycoprotein that was originally isolated from bone. Its molecular weights have been reported in the range of 66 kDa to 44 kDa depending on glycosylation and phosphorylation. OPN is also known to be expressed in other fluids and tissues including milk, urine, activated T cells, smooth muscle cells, kidney and some tumor cells. OPN contains an ArgGlyAsp (RGD) amino acid sequence. This motif is present in fibronectin, vitronectin and a variety of other extracellular proteins that bind members of the integrin family of cell surface receptors such as avbeta3. OPN was also identified as a ligand for CD44, the levels of which correlate with aggressiveness of lymphoid tumors and invasiveness of bladder carcinoma. Its interaction does not require the RGD motif of OPN. In OPN knockout mice, it has been reported that a significantly decreased level of debridement was shown.
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。