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当前位置: 首页 > 产品中心 > monoclonal_antibody > Fitzgerald/Osteopontin N Half antibody/10R-3058/100 ug
商品详细Fitzgerald/Osteopontin N Half antibody/10R-3058/100 ug
Fitzgerald/Osteopontin N Half antibody/10R-3058/100 ug
Fitzgerald/Osteopontin N Half antibody/10R-3058/100 ug
商品编号: 10R-3058-100ug
品牌: fitzgerald-fii
市场价: ¥13500.00
美元价: 10125.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

OVERVIEW:

Synonyms Monoclonal osteopontin antibody, Anti-Osteopontin antibody, BNSP antibody, Bone Sialoprotein 1 antibody, OPN antibody, Uropontin antibody, Bone Sialoprotein 1 antibody, Nephropontin antibody, Secreted Phosphoprotein 1 antibody, Urinary Stone protein antibody, SPP-1 antibody, Urinary Stone protein antibody, Uropontin antibody, osteopontin antibody, Anti Osteopontin antibody, , , OPN antibody, Nephropontin antibody, BNSP antibody, SPP-1 antibody, Secreted Phosphoprotein 1 antibody
Cross Reactivity To be determined by end-user
Applications WB
Immunogen OPN antibody was raised in mouse using a synthetic peptide for a part of human osteopontin (SVVYGLR) as the immunogen

SPECIFICATIONS:

Host Mouse
Clone 34E3
Isotype IgG1
Source Supernatant
Form & Buffer Lyophilized product from 1% BSA in PBS containing 0.05% NaN3

STORAGE & SAFETY:

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at 20 deg C for long term storage

GENERAL INFORMATION:

Biological Significance Osteopontin (OPN) is a secreted glycoprotein that was originally isolated from bone. Its molecular weights have been reported in the range of 66 kDa to 44 kDa depending on glycosylation and phosphorylation. OPN is also known to be expressed in other fluids and tissues including milk, urine, activated T cells, smooth muscle cells, kidney and some tumor cells. OPN contains an ArgGlyAsp (RGD) amino acid sequence. This motif is present in fibronectin, vitronectin and a variety of other extracellular proteins that bind members of the integrin family of cell surface receptors such as avbeta3. OPN was also identified as a ligand for CD44, the levels of which correlate with aggressiveness of lymphoid tumors and invasiveness of bladder carcinoma. Its interaction does not require the RGD motif of OPN. In OPN knockout mice, it has been reported that a significantly decreased level of debridement was shown.
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。