Fitzgerald/Parkin antibody/10R-3062/100 ug
商品编号：
10R-3062-100ug
品牌：
fitzgerald-fii
市场价：
¥13500.00
美元价：
10125.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal Parkin antibody, Anti-Parkin antibody, PRKN 2 antibody, FRA6E antibody, Parkinson disease (autosomal recessive juvenile) 2 antibody, E3 ubiquitin protein ligase parkin antibody, PRKN2 antibody, Anti Parkin antibody, Parkinson juvenile disease protein 2 antibody, LPRS2 antibody, Parkinson disease (autosomal recessive juvenile) 2 antibody, PDJ antibody, E3 ubiquitin protein ligase parkin antibody, FRA6E antibody, PDJ antibody, AR JP antibody, Parkin antibody, Parkinson juvenile disease protein 2 antibody, Parkinson disease protein 2 antibody, Ubiquitin E3 ligase PRKN antibody, LPRS 2 antibody, LPRS2 antibody, PARK 2 antibodyPARK2 antibody, AR JP antibody, Parkinson disease protein 2 antibody, PRKN antibody, PRKN 2 antibody, PARK 2 antibodyPARK2 antibody, Ubiquitin E3 ligase PRKN antibody , PRKN antibody, LPRS 2 antibody, PRKN2 antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | To be determined by end-user |
| Applications | IHC, IP, WB |
| Immunogen | Parkin antibody was raised in mouse using a synthetic peptide corresponding to the Cterminal part of human parkin (AYRVDERAAEQARWEAA) as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 5A1 |
| Isotype | IgG1 |
| Source | Supernatant |
| Method of Purification | Parkin antibody was affinity purified with antigen peptide |
| Form & Buffer | Lyophilized product from 1% BSA in PBS containing 0.05% NaN3 reconstitute with 1 ml of dEionised water |
STORAGE & SAFETY:
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at 20 deg C for long term storage |
|---|
Usage Assay Information:
| Usage Recommendations | IHC: 5 ug/ml, IP: 3 ug/ml, WB: 5 ug/ml |
|---|
GENERAL INFORMATION:
| Biological Significance | Parkinson's Disease (PD) is a relatively common neurodegenerative disorder, which is characterized by the loss of midbrain dopamine (DA) neurons and the presence of Lewy bodies, proteinaceous cytoplasmic inclusions that are abundantly enriched in ubiquitin. A number of potential substrates for parkin, which may be involved in the pathogenesis of PD, have been identified. Autosomal Recessive Juvenile Parkinsonism (ARJP) is a recently described form of Parkinson?s Disease that has been linked to a gene that codes for parkin. Parkin, a 52 kDa protein, has a suggested role in the ubiquitin/proteasome pathway for protein degradation. The amino terminus bears sequence homology to ubiquitin while functionally it acts as a RING-type ubiquitin protein ligase (E3) that coordinates the transfer of ubiquitin to substrate proteins, thus targeting them for degradation by the proteasome. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
联络我们
