Fitzgerald/TIE1 antibody/10R-3075/100 ug
商品编号：
10R-3075-100ug
品牌：
fitzgerald-fii
市场价：
¥13900.00
美元价：
10425.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal TIE1 antibody, Anti-TIE1 antibody, TIE-1 antibody, Tyrosine kinase with immunoglobulin-like and EGF-like domains 1 antibody, Tie-1, Tie-1 antibody, Tie 1 antibody, Tie 1, Tie1, TIE 1 antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | To be determined by end-user |
| Applications | FCM, IP, WB |
| Immunogen | Tie1 antibody was raised in mouse using a recombinant protein corresponding to the extracellular domain of human Tie1 as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 9C1 |
| Isotype | IgG2a |
| Source | Supernatant |
| Method of Purification | TIE1 antibody was affinity purified with protein A |
| Form & Buffer | Lyophilized product from 1% BSA in PBS containing 0.05% NaN3, reconstitute with 1 ml of deionised water |
STORAGE & SAFETY:
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at 20 deg C for long term storage |
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Usage Assay Information:
| Usage Recommendations | FACS: 0.10.5 ug/1×10^5 cells IP: 35 ug/test, WB: 15 ug/ml |
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GENERAL INFORMATION:
| Biological Significance | TIE is a new receptor-type tyrosine kinase that was cloned from K562, a chronic myelocytic leukemia cell line. Its molecular weight is 117 kDa and its structure begins with an immunoglobulin-like domain from the extracellular N terminal, continues to 3 EGF-like domains, another immunoglobulin-like domain, 3 fibronectin III-like domains, a membrane-penetrating domain, 2 tyrosine kinase domains and a C-terminal domain. It has been reported that Tek molecules with a high homology (about 80%) have been cloned from the kinase domains. These molecules are believed to make up a Tie family. Tie2 and a receptor type tyrosine kinase Tie1 that is expressed specifically in endothelial cells are included in this Tie family. Among the Tie1 gene knockout mice, a vasculature is formed in a homozygote (/) but the mouse is likely to succumb to pulmonary edema. Thus it has been reported that the signal via Tie1 is important in maintaining the vascular structure. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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