Fitzgerald/BTRC antibody/10R-3512/100 ul
商品编号:
10R-3512-100ul
品牌:
fitzgerald-fii
市场价:
¥12240.00
美元价:
9180.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | Monoclonal BTRC antibody, Anti-BTRC antibody, Beta-transducin repeat containing antibody, FBXW1A antibody, bTrCP antibody, bTrCP1 antibody, E3RSIkappaB antibody, pIkappaBalpha-E3 receptor subunit antibody, Fwd1 antibody, FBW1A antibody |
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Cross Reactivity | Human |
Applications | WB |
Immunogen | BTRC antibody was raised in mouse using a human fragment corresponding to amino acids 52-354 of human BTRC (NP_378663) produced in E. coli as the immunogen. |
SPECIFICATIONS:
Host | Mouse |
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Clone | 1F3 |
Isotype | IgG1 |
Method of Purification | BTRC antibody was purified by affinity chromatography. |
Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 500 ug-1 mg/ml |
STORAGE & SAFETY:
Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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Usage Assay Information:
Usage Recommendations | WB: 1:500 |
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GENERAL INFORMATION:
Biological Significance | BTRC is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs(SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitin ation. The F-box proteins are divided into 3classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either differentprotein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbwsclass; in addition to an F-box, this protein contains multiple WD-40 repeats. This protein is homologous to XenopusbTrCP1, yeast Met30, Neurospora Scon2 and Drosophila Slimb proteins. It interacts with HIV-1 Vpu and connects CD4 tothe proteolytic machinery. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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