Fitzgerald/CCM2 antibody/10R-3599/100 ul
商品编号：
10R-3599-100ul
品牌：
fitzgerald-fii
市场价：
¥12240.00
美元价：
9180.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal CCM2 antibody, Anti-CCM2 antibody, Cerebral cavernous malformation 2 antibody, C7orf22 antibody, MGC4607 antibody, Cerebral cavernous malformations 2 protein antibody, MGC4067 antibody, Chromosome 7 open reading frame 22 antibody, Malcavernin antibody, CCM2, CCM 2, CCM-2, CCM 2 antibody, CCM-2 antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | IF, WB |
| Immunogen | CCM2 antibody was raised in mouse using a full length recombinant protein of human CCM2 (NP_113631) produced in HEK293T cells, as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 5H4 |
| Isotype | IgG2b |
| Method of Purification | CCM2 antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 500 ug-1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | IF: 1:100, WB: 1:2000 |
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GENERAL INFORMATION:
| Biological Significance | CCM2 is a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK)signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via aphosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. . |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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