菲茨杰拉德/CHEK2抗体/10R-3683/100微升
商品编号：
10R-3683-100ul
品牌：
fitzgerald-fii
市场价：
¥12240.00
美元价：
9180.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal CHEK2 antibody, Anti-CHEK2 antibody, CHK2 checkpoint homolog antibody, CHK2 antibody, CDS1 antibody, RAD53 antibody, HuCds1 antibody, PP1425 antibody, LFS2 antibody, bA444G7 antibody, Protein kinase CHK2 antibody, Cds1 antibody, CHEK2, CHEK 2, CHEK-2, CHEK 2 antibody, CHEK-2 antibody |
|---|---|
| Cross Reactivity | Human, Dog, Monkey |
| Applications | FC, IHC, WB |
| Immunogen | CHEK2 antibody was raised in mouse using a full length recombinant protein of human CHEK2 (NP_009125) produced in HEK293T cells, as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 8D11 |
| Isotype | IgG1 |
| Method of Purification | CHEK2 antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 500 ug-1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | FC: 1:100, IF 1:50-100, WB: 1:500-1000 |
|---|
GENERAL INFORMATION:
| Biological Significance | CHEK2 regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strandbreaks. CHEK2 also inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. It regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20' |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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