Fitzgerald/DAND5 antibody/10R-3803/100 ul
商品编号：
10R-3803-100ul
品牌：
fitzgerald-fii
市场价：
¥12880.00
美元价：
9660.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal DAND5 antibody, Anti-DAND5 antibody, DAN domain family member 5 antibody, CER2 antibody, CKTSF1B3 antibody, GREM3 antibody, DANTE antibody, Cerberus like protein 2 antibody, Cysteine knot superfamily 1 BMP antagonist 3 antibody, DAND5, DAND 5, DAND-5, DAND 5 antibody, DAND-5 antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | FC, IHC, WB |
| Immunogen | DAND5 antibody was raised in mouse using a human recombinant protein fragment corresponding to amino acids 23-189 of human DAND5 (NP_689867) produced in E. coli as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 2H3 |
| Isotype | IgG1 |
| Method of Purification | DAND5 antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 500 ug-1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | FC: 1:100, IHC: 1:150, WB: 1:500-2000 |
|---|
GENERAL INFORMATION:
| Biological Significance | DAND5 is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists containcystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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