Fitzgerald/IFT57 antibody/10R-4441/100 ul
商品编号：
10R-4441-100ul
品牌：
fitzgerald-fii
市场价：
¥12240.00
美元价：
9180.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal IFT57 antibody, Anti-IFT57 antibody, Intraflagellar transport 57 homolog antibody, HIPPI antibody, MHS4R2 antibody, ESRRBL1 antibody, Estrogen related receptor beta like 1 antibody, Dermal papilla derived protein 8 antibody, Huntingtin interacting protein 1 interacting protein antibody, IFT57, IFT 57, IFT-57, IFT 57 antibody, IFT-57 antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | IHC |
| Immunogen | IFT57 antibody was raised in mouse using a full length recombinant protein of human IFT57 (NP_060480) produced in HEK293T cells, as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 5B6 |
| Isotype | IgG1 |
| Method of Purification | IFT57 antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 500 ug-1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | IHC: 1:50, WB: 1:500 |
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GENERAL INFORMATION:
| Biological Significance | IFT57 is required for the formation of cilia. It plays an indirect role in sonic hedgehog signaling, cilia being requiredfor all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3'present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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