Fitzgerald/LDHA antibody/10R-4599/100 ul
商品编号:
10R-4599-100ul
品牌:
fitzgerald-fii
市场价:
¥12240.00
美元价:
9180.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | Monoclonal LDHA antibody, Anti-LDHA antibody, GSD11 antibody, LDH1 antibody, LDHM antibody, PIG19 antibody, L-lactate dehydrogenase A chain Cell proliferation-inducing gene 19 protein antibody, LDH muscle subunit antibody, M LDH antibody, L lactate dehydrogenase A chain antibody, l7R2 antibody, Lactate dehydrogenase 1 antibody, A chain antibody, Lactate dehydrogenase A antibody, Lactate dehydrogenase A4 antibody, Lactate dehydrogenase M antibody, LDH muscle subunit antibody, OTTMUSP00000017774 antibody, Monoclonal LDHA antibody, Anti-LDHA antibody, GSD11 antibody, LDH1 antibody, LDHM antibody, PIG19 antibody, L-lactate dehydrogenase A chain Cell proliferation-inducing gene 19 protein antibody, LDH muscle subunit antibody, M LDH antibody, L lactate dehydrogenase A chain antibody, l7R2 antibody, Lactate dehydrogenase 1 antibody, A chain antibody, Lactate dehydrogenase A antibody, Lactate dehydrogenase A4 antibody, Lactate dehydrogenase M antibody, LDH muscle subunit antibody, OTTMUSP00000017774 antibody |
---|---|
Cross Reactivity | Human |
Applications | IHC, WB |
Immunogen | LDHA antibody was raised in mouse using a protein expressed in 293T cell transfected with human LDHA expression vector as the immunogen. |
SPECIFICATIONS:
Host | Mouse |
---|---|
Clone | 2D11 |
Isotype | IgG1 |
Method of Purification | LDHA antibody was purified by affinity chromatography. |
Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 500 ug-1 mg/ml |
STORAGE & SAFETY:
Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
---|
Usage Assay Information:
Usage Recommendations | IHC: 1:50, WB: 1:1000 |
---|
GENERAL INFORMATION:
Biological Significance | LDHA which is encoded by a target gene of c-Myc and hypoxia-inducible factor (HIF-1). LDHA expression is repressed by SugR in the absence of sugar. Reduction of LDHA causes bioenergetic and oxidative stress leading to cell death. LDHA (LDH-5, M-LDH, or A4), which is the predominant form in skeletal muscle, kinetically favors the conversion of pyruvate to lactate. Therefore, LDH-A is an attractive target for cancer therapy since its expression is largely relegated to skeletal muscle. |
---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
联络我们