Fitzgerald/LDLRAP1 antibody/10R-4608/100 ul
商品编号：
10R-4608-100ul
品牌：
fitzgerald-fii
市场价：
¥7900.00
美元价：
5925.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal LDLRAP1 antibody, Anti-LDLRAP1 antibody, Low Density Lipoprotein Receptor Adaptor Protein 1 antibody, ARH antibody, ARH1 antibody, ARH2 antibody, DKFZp586D0624 antibody, FHCB1 antibody, FHCB2 antibody, MGC34705 antibody, LDLRAP1, LDLRAP 1, LDLRAP-1, LDLRAP 1 antibody, LDLRAP-1 antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | FC, WB |
| Immunogen | LDLRAP1 antibody was raised in mouse using a full length recombinant protein of human LDLRAP1 (NP_056442) produced in HEK293T cells, as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 5A12 |
| Isotype | IgG1 |
| Method of Purification | LDLRAP1 antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 500 ug-1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | FC: 1:100, WB: 1:2000 |
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GENERAL INFORMATION:
| Biological Significance | LDLRAP1 is an adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). LDLRAP1 may be required for LDL binding and internalization but not for receptor clustering in coated pits. LDLRAP1 may facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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