Fitzgerald/MAP2K2 antibody/10R-4738/100 ul
商品编号：
10R-4738-100ul
品牌：
fitzgerald-fii
市场价：
¥12240.00
美元价：
9180.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal MAP2K2 antibody, Anti-MAP2K2 antibody, Mitogen-Activated Protein Kinase 2 antibody, MAPKK2 antibody, MEK2 antibody, MKK2 antibody, PRKMK2 antibody, MAP2K2, MAPK 2, MAPK-2, MAPK 2 antibody, MAPK-2 antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | IHC, WB |
| Immunogen | MAP2K2 antibody was raised in mouse using a protein expressed in 293T cell transfected with human MAP2K2 expression vector as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 5F6 |
| Isotype | IgG1 |
| Method of Purification | MAP2K2 antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 500 ug-1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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Usage Assay Information:
| Usage Recommendations | IHC: 1:50, WB: 1:2000 |
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GENERAL INFORMATION:
| Biological Significance | MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in MAP2K2 gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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