Fitzgerald/MAPK8 antibody/10R-4773/100 ul
商品编号:
10R-4773-100ul
品牌:
fitzgerald-fii
市场价:
¥12880.00
美元价:
9660.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | Monoclonal MAPK8 antibody, Anti-MAPK8 antibody, Mitogen activated protein kinase 8 antibody, JNK1 antibody, SAPK1 antibody, PRKM8 antibody, JNK antibody, Stress-activated protein kinase 1 antibody, JNK1 alpha protein kinase antibody, MAPK8, MAPK 8, MAPK-8, MAPK 8 antibody, MAPK-8 antibody |
---|---|
Cross Reactivity | Human |
Applications | WB |
Immunogen | MAPK8 antibody was raised in mouse using a recombinant protein expressed in E. coli corresponding to amino acids 1-384 of human JNK1 as the immunogen. |
SPECIFICATIONS:
Host | Mouse |
---|---|
Clone | 2F10 |
Isotype | IgG2a |
Method of Purification | MAPK8 antibody was purified by affinity chromatography. |
Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 500 ug-1 mg/ml |
STORAGE & SAFETY:
Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
---|
Usage Assay Information:
Usage Recommendations | WB: 1:1000 |
---|
GENERAL INFORMATION:
Biological Significance | MAPK8 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha inducedapoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochromc-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a keyrole in T cell proliferation, apoptosis and differentiation. |
---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
联络我们