Fitzgerald/NSMCE2 antibody/10R-5051/100 ul
商品编号：
10R-5051-100ul
品牌：
fitzgerald-fii
市场价：
¥12880.00
美元价：
9660.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal NSMCE2 antibody, Anti-NSMCE2 antibody, Non-Smc Element 2 Mms21 Homolog antibody, C8orf36 antibody, FLJ32440 antibody, MMS21 antibody, NSE2 antibody, NSMCE2, NSMCE 2, NSMCE-2, NSMCE 2 antibody, NSMCE-2 antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | FC, IF, WB |
| Immunogen | NSMCE2 antibody was raised in mouse using a full length recombinant protein of human NSMCE2 (NP_775956) produced in E. coli as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 6A6 |
| Isotype | IgG2a |
| Method of Purification | NSMCE2 antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 500 ug-1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | FC: 1:100, IF: 1:100, WB: 1:2000 |
|---|
GENERAL INFORMATION:
| Biological Significance | NSMCE2 is the E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. NSMCE2 acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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