Fitzgerald/RIC8A antibody/10R-5623/100 ul
商品编号：
10R-5623-100ul
品牌：
fitzgerald-fii
市场价：
¥9100.00
美元价：
6825.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal RIC8A antibody, Anti-RIC8A antibody, Resistance To Inhibitors Of Cholinesterase 8 Homolog A antibody, MGC104517 antibody, MGC131931 antibody, MGC148073 antibody, MGC148074 antibody, RIC8 antibody, synembryn antibody, RIC8A, RICA 8, RICA-8, RICA 8 antibody, RICA-8 antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | IF, IHC, WB |
| Immunogen | RIC8A antibody was raised in mouse using a full length recombinant protein of human RIC8A (NP_068751) produced in HEK293T cells, as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 3G3 |
| Isotype | IgG1 |
| Method of Purification | RIC8A antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 500 ug-1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | IF: 1:100, IHC: 1:50, WB: 1:1000 |
|---|
GENERAL INFORMATION:
| Biological Significance | RIC8A is a guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. RIC8A is able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. RIC8A is involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. RIC8A also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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