菲茨杰拉德/TP53抗体/10R-6106/100微升
商品编号：
10R-6106-100ul
品牌：
fitzgerald-fii
市场价：
¥12240.00
美元价：
9180.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal TP53 antibody, Anti-TP53 antibody, Tumor protein p53 antibody, LFS1 antibody, P53 antibody, Antigen NY-CO-13 antibody, Phosphoprotein p53 antibody, Cellular tumor antigen p53 antibody, Tumor suppressor p53 antibody, TP53, TP 53, TP-53, TP 53 antibody, TP-53 antibody |
|---|---|
| Cross Reactivity | Human, Monkey |
| Applications | FC, IF, WB |
| Immunogen | TP53 antibody was raised in mouse using a full length recombinant protein of human TP53 (NP_000537) produced in HEK293T cells, as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 5D9 |
| Isotype | IgG1 |
| Method of Purification | TP53 antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 500 ug-1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
Usage Assay Information:
| Usage Recommendations | FC: 1:100, IF: 1:100, WB: 1:500-2000 |
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GENERAL INFORMATION:
| Biological Significance | This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, andoligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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