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当前位置: 首页 > 产品中心 > Functional_antibody > Fitzgerald/TRPM4 antibody/10R-6142/100 ul
商品详细Fitzgerald/TRPM4 antibody/10R-6142/100 ul
Fitzgerald/TRPM4 antibody/10R-6142/100 ul
Fitzgerald/TRPM4 antibody/10R-6142/100 ul
商品编号: 10R-6142-100ul
品牌: fitzgerald-fii
市场价: ¥12240.00
美元价: 9180.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

OVERVIEW:

Synonyms Monoclonal TRPM4 antibody, Anti-TRPM4 antibody, Transient Receptor Potential Cation Channel Subfamily M Member 4 antibody, FLJ20041 antibody, TRPM4B antibody, TRPM4, TRPM 4, TRPM-4, TRPM 4 antibody, TRPM-4 antibody
Cross Reactivity Human
Applications IHC, WB
Immunogen TRPM4 antibody was raised in mouse using a protein expressed in 293T cell transfected with human TRPM4 expression vector as the immunogen.

SPECIFICATIONS:

Host Mouse
Clone 14F1
Isotype IgG1
Method of Purification TRPM4 antibody was purified by affinity chromatography.
Form & Buffer Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 500 ug-1 mg/ml

STORAGE & SAFETY:

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Usage Assay Information:

Usage Recommendations IHC: 1:50, WB: 1:1000

GENERAL INFORMATION:

Biological Significance TRPM4 is a calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca2+, it is impermeable to it. TRPM4 mediates transport of monovalent cations (Na+ > K+ > Cs+ > Li+), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhin al cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca2+ oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production.
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。