Fitzgerald/NFkB p65 antibody/10R-6718/100 ug
商品编号:
10R-6718-100ug
品牌:
fitzgerald-fii
市场价:
¥12700.00
美元价:
9525.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | Monoclonal NFkB p65 antibody, Anti-NFkB p65 antibody, NFkB-p65 antibody, NF-kappaB antibody, NFkappaB antibody, Nuclear factor NF-kappa-B p65 subunit antibody, Monoclonal NFkB p65 antibody, Anti-NFkB p65 antibody, NFkB-p65 antibody, NF-kappaB antibody, NFkappaB antibody, Nuclear factor NF-kappa-B p65 subunit antibody |
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Cross Reactivity | Human, Mouse, Rat |
Applications | IHC, IP, WB |
Immunogen | NFkB p65 antibody was raised in Mouse using synthetic peptide from human NFkB as the immunogen. |
SPECIFICATIONS:
Host | Mouse |
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Clone | S-8 |
Isotype | IgG1 |
Form & Buffer | Supplied in PBS containing 1 mg/ml BSA and 1.5 mM sodium azide and 50% glycerol. |
Concentration | 200 ug/ml |
STORAGE & SAFETY:
Storage | Store at -20 deg C. For long-term storage, aliquot and freeze at -70 deg C. Avoid repeated freeze/thaw cycles. |
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Usage Assay Information:
Usage Recommendations | WB: 1-4 ug/ml |
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GENERAL INFORMATION:
Biological Significance | NFkB was identified as a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NFkB is a heterodimer that consists of a 50 kDa DNA binding subunit (p50) and a 65 kDa transactivation subunit (p65/RelA). Both of these subunits exhibit sequence homology to the protooncogene c Rel. The p50/p65 heterodimer remains in the cytosol in an inactive form as a complex with its inhibitor, IkB. Upon stimulation of cells by a wide variety of stimuli such as lipopolysaccharide (LPS), pro inflammatory cytokines, and viral infection. IkB is phosphorylated and degraded by proteosome. The active NFkB heterodimer is translocated into the nucleus and induces gene expression. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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